Liposomes are the small vessels shaped like a bubble that are composed of exactly the same material as a cell membrane. The membranes themselves are composed of lipids known as phospholipids, split into three sections, they have one head that is highly attracted to water and then two different hydrocarbon chained tails that have the opposite effect on water. These cells, with the help of liposomes, help deliver drugs to the system to fight illnesses.
These phospholipids, made up of lipids found in the plasma membrane, can be found in stable bilayer membranes, which means that they are made up of two different layers. When they are in water, the heads, which are hydrophilic, will line up together, facing the direction of the water, whereas the tails, being hydrophobic, will line up facing the opposite direction of the water as they are repelled by it.
In a cell, when this happens, the phospholipid heads will form a layer by lining up together facing the outer wall of the cell, being attracted to the surrounding water in the environment, with another line of heads facing the inner core of the cell and the water found there. By doing this, the hydrocarbon tails of both lines join together, which forms the bilayer and completing it.
Liposomes are created when one of these membrane phospholipids are disrupted and thy reassemble themselves into small spheres, in either bilayers, which are known as lipsomes, or in monolayers known as micelles, these spheres are always smaller than the original and normal cell.
Both phospholipids that are naturally derived, containing lipid chains that are mixed, and components from pure surfactants can create a liposome. The liposome itself will normally have a core made from an aqueous solution, therefore defining what it is, otherwise they would be called micelles. A liposome can come in different sizes.
Liposomes have been used over the years for drug deliveries to the body, due to the unique properties that they have. They can encapsulate a region on the aqueous solutions, in a membrane that is hydrophobic, this is because a hydrophilic solution can not go through a lipid without the help of a dis-solvent. This can be done with the three different types of liposome, which are the MLV, the SUV and the LUV liposome.
Thanks to being able to carry within them both types of molecules, the hydrophobic and hydrophilic, they can be placed straight into the body of a membrane. When the lipid bilayer is fused with other bilayers the molecules and the content of the liposomes can be delivered directly to the affected area. Being delivered straight past any bilayers when used as DNA or drugs.
Liposomes are used as models or substitutes to artificial cells and can be used to be able to deliver drugs in a variety of ways and help by delivering the drugs by diffusion instead of by cell fusion and are very easily digested by the system. And they can also be used as different carriers to deliver dyes to cloths, plant pesticides, cosmetics and supplements in foods.
These phospholipids, made up of lipids found in the plasma membrane, can be found in stable bilayer membranes, which means that they are made up of two different layers. When they are in water, the heads, which are hydrophilic, will line up together, facing the direction of the water, whereas the tails, being hydrophobic, will line up facing the opposite direction of the water as they are repelled by it.
In a cell, when this happens, the phospholipid heads will form a layer by lining up together facing the outer wall of the cell, being attracted to the surrounding water in the environment, with another line of heads facing the inner core of the cell and the water found there. By doing this, the hydrocarbon tails of both lines join together, which forms the bilayer and completing it.
Liposomes are created when one of these membrane phospholipids are disrupted and thy reassemble themselves into small spheres, in either bilayers, which are known as lipsomes, or in monolayers known as micelles, these spheres are always smaller than the original and normal cell.
Both phospholipids that are naturally derived, containing lipid chains that are mixed, and components from pure surfactants can create a liposome. The liposome itself will normally have a core made from an aqueous solution, therefore defining what it is, otherwise they would be called micelles. A liposome can come in different sizes.
Liposomes have been used over the years for drug deliveries to the body, due to the unique properties that they have. They can encapsulate a region on the aqueous solutions, in a membrane that is hydrophobic, this is because a hydrophilic solution can not go through a lipid without the help of a dis-solvent. This can be done with the three different types of liposome, which are the MLV, the SUV and the LUV liposome.
Thanks to being able to carry within them both types of molecules, the hydrophobic and hydrophilic, they can be placed straight into the body of a membrane. When the lipid bilayer is fused with other bilayers the molecules and the content of the liposomes can be delivered directly to the affected area. Being delivered straight past any bilayers when used as DNA or drugs.
Liposomes are used as models or substitutes to artificial cells and can be used to be able to deliver drugs in a variety of ways and help by delivering the drugs by diffusion instead of by cell fusion and are very easily digested by the system. And they can also be used as different carriers to deliver dyes to cloths, plant pesticides, cosmetics and supplements in foods.
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